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In some instances, vapor pressure depression method allows for determination of the osmolarity of a formulation comprising a gelling agent (e.g., a thermoreversible polymer) at a higher temperature wherein the gelling agent is in the form of a gel

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At this low concentration, it doesnt alter peptide folding or bioactivity for the vast majority of research compounds unlike harsher preservatives or mismatched solvents that might cause precipitation or reduced efficacy